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SELECT 
  a.variant_id, 
  a.option_id, 
  a.position, 
  a.modifier, 
  a.modifier_type, 
  a.weight_modifier, 
  a.weight_modifier_type, 
  a.point_modifier, 
  a.point_modifier_type, 
  b.variant_name, 
  IF(
    shared_option_variants.variant_id IS NOT NULL, 
    shared_option_variants.modifier, 
    a.modifier
  ) as modifier, 
  IF(
    shared_option_variants.variant_id IS NOT NULL, 
    shared_option_variants.modifier_type, 
    a.modifier_type
  ) as modifier_type 
FROM 
  cscart_product_option_variants as a 
  LEFT JOIN cscart_product_option_variants_descriptions as b ON a.variant_id = b.variant_id 
  AND b.lang_code = 'it' 
  LEFT JOIN cscart_ult_product_option_variants shared_option_variants ON shared_option_variants.variant_id = a.variant_id 
  AND shared_option_variants.company_id = 1 
WHERE 
  a.option_id IN (
    219, 355, 413, 471, 4152, 332, 4163, 3878, 
    3880, 3882, 2381, 2441, 2501, 163, 171, 
    179, 547, 2383, 2443, 2503
  ) 
  AND a.status = 'A' 
ORDER BY 
  a.position, 
  a.variant_id

Query time 0.00121

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "103.21"
    },
    "ordering_operation": {
      "using_filesort": true,
      "cost_info": {
        "sort_cost": "32.00"
      },
      "nested_loop": [
        {
          "table": {
            "table_name": "shared_option_variants",
            "access_type": "system",
            "possible_keys": [
              "PRIMARY",
              "company_id"
            ],
            "rows_examined_per_scan": 0,
            "rows_produced_per_join": 1,
            "filtered": "0.00",
            "const_row_not_found": true,
            "cost_info": {
              "read_cost": "0.00",
              "eval_cost": "0.20",
              "prefix_cost": "0.00",
              "data_read_per_join": "24"
            },
            "used_columns": [
              "variant_id",
              "company_id",
              "modifier",
              "modifier_type"
            ]
          }
        },
        {
          "table": {
            "table_name": "a",
            "access_type": "range",
            "possible_keys": [
              "status",
              "option_id",
              "option_id_2"
            ],
            "key": "option_id",
            "used_key_parts": [
              "option_id",
              "status"
            ],
            "key_length": "6",
            "rows_examined_per_scan": 32,
            "rows_produced_per_join": 32,
            "filtered": "100.00",
            "index_condition": "((`eshopuga_upgr_4122`.`a`.`option_id` in (219,355,413,471,4152,332,4163,3878,3880,3882,2381,2441,2501,163,171,179,547,2383,2443,2503)) and (`eshopuga_upgr_4122`.`a`.`status` = 'A'))",
            "cost_info": {
              "read_cost": "58.41",
              "eval_cost": "6.40",
              "prefix_cost": "64.81",
              "data_read_per_join": "1K"
            },
            "used_columns": [
              "variant_id",
              "option_id",
              "position",
              "modifier",
              "modifier_type",
              "weight_modifier",
              "weight_modifier_type",
              "point_modifier",
              "point_modifier_type",
              "status"
            ]
          }
        },
        {
          "table": {
            "table_name": "b",
            "access_type": "eq_ref",
            "possible_keys": [
              "PRIMARY"
            ],
            "key": "PRIMARY",
            "used_key_parts": [
              "variant_id",
              "lang_code"
            ],
            "key_length": "9",
            "ref": [
              "eshopuga_upgr_4122.a.variant_id",
              "const"
            ],
            "rows_examined_per_scan": 1,
            "rows_produced_per_join": 32,
            "filtered": "100.00",
            "cost_info": {
              "read_cost": "0.00",
              "eval_cost": "6.40",
              "prefix_cost": "71.21",
              "data_read_per_join": "24K"
            },
            "used_columns": [
              "variant_id",
              "lang_code",
              "variant_name"
            ]
          }
        }
      ]
    }
  }
}

Result

variant_id	option_id	position	modifier	modifier_type	weight_modifier_type	point_modifier_type	variant_name
550	163	0	0.000	A	A	A	Vanilla (Brown)
551	163	0	0.000	A	A	A	Lemon
552	163	0	0.000	A	A	A	Coconut
553	163	0	0.000	A	A	A	Orange
554	163	0	0.000	A	A	A	Fruit Cake
578	171	0	1.000	A	A	A	10x4
579	171	0	4.000	A	A	A	11x4
580	171	0	10.000	A	A	A	12X4
748	332	0	0.000	A	A	A
788	355	0	0.000	A	A	A
904	413	0	0.000	A	A	A
2250	2441	0	0.000	A	A	A
2254	2443	0	0.000	A	A	A
3250	3880	0	0.000	A	A	A
747	332	1	2.000	A	A	A
787	355	1	9.000	A	A	A
903	413	1	2.000	A	A	A
2249	2441	1	2.000	A	A	A
2253	2443	1	2.000	A	A	A
3249	3880	1	2.000	A	A	A