SELECT 
  a.variant_id, 
  a.option_id, 
  a.position, 
  a.modifier, 
  a.modifier_type, 
  a.weight_modifier, 
  a.weight_modifier_type, 
  a.point_modifier, 
  a.point_modifier_type, 
  b.variant_name, 
  IF(
    shared_option_variants.variant_id IS NOT NULL, 
    shared_option_variants.modifier, 
    a.modifier
  ) as modifier, 
  IF(
    shared_option_variants.variant_id IS NOT NULL, 
    shared_option_variants.modifier_type, 
    a.modifier_type
  ) as modifier_type 
FROM 
  cscart_product_option_variants as a 
  LEFT JOIN cscart_product_option_variants_descriptions as b ON a.variant_id = b.variant_id 
  AND b.lang_code = 'it' 
  LEFT JOIN cscart_ult_product_option_variants shared_option_variants ON shared_option_variants.variant_id = a.variant_id 
  AND shared_option_variants.company_id = 1 
WHERE 
  a.option_id IN (
    330, 248, 334, 335, 4150, 332, 4161, 4151, 
    4162, 2843, 2844, 2845, 2846, 2851, 
    2849, 2850, 2853, 4171, 2852, 4170, 
    4169, 2854, 2838, 2839, 2840, 2841, 
    4152, 4163, 143, 333, 4153, 4164, 4155, 
    4166, 254, 388, 446, 504, 234, 370, 428, 
    486, 221, 357, 415, 473, 4149, 4160, 
    228, 364, 422, 480, 262, 394, 452, 510, 
    246, 382, 440, 498, 267, 533, 534, 535, 
    206, 342, 400, 458, 268, 518, 519, 520, 
    257, 391, 449, 507, 216, 352, 410, 468, 
    233, 369, 427, 485
  ) 
  AND a.status = 'A' 
ORDER BY 
  a.position, 
  a.variant_id

Query time 0.00289

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "617.01"
    },
    "ordering_operation": {
      "using_filesort": true,
      "cost_info": {
        "sort_cost": "205.00"
      },
      "nested_loop": [
        {
          "table": {
            "table_name": "shared_option_variants",
            "access_type": "system",
            "possible_keys": [
              "PRIMARY",
              "company_id"
            ],
            "rows_examined_per_scan": 0,
            "rows_produced_per_join": 1,
            "filtered": "0.00",
            "const_row_not_found": true,
            "cost_info": {
              "read_cost": "0.00",
              "eval_cost": "0.20",
              "prefix_cost": "0.00",
              "data_read_per_join": "24"
            },
            "used_columns": [
              "variant_id",
              "company_id",
              "modifier",
              "modifier_type"
            ]
          }
        },
        {
          "table": {
            "table_name": "a",
            "access_type": "range",
            "possible_keys": [
              "status",
              "option_id",
              "option_id_2"
            ],
            "key": "option_id",
            "used_key_parts": [
              "option_id",
              "status"
            ],
            "key_length": "6",
            "rows_examined_per_scan": 205,
            "rows_produced_per_join": 205,
            "filtered": "100.00",
            "index_condition": "((`eshopuga_upgr_4122`.`a`.`option_id` in (330,248,334,335,4150,332,4161,4151,4162,2843,2844,2845,2846,2851,2849,2850,2853,4171,2852,4170,4169,2854,2838,2839,2840,2841,4152,4163,143,333,4153,4164,4155,4166,254,388,446,504,234,370,428,486,221,357,415,473,4149,4160,228,364,422,480,262,394,452,510,246,382,440,498,267,533,534,535,206,342,400,458,268,518,519,520,257,391,449,507,216,352,410,468,233,369,427,485)) and (`eshopuga_upgr_4122`.`a`.`status` = 'A'))",
            "cost_info": {
              "read_cost": "330.01",
              "eval_cost": "41.00",
              "prefix_cost": "371.01",
              "data_read_per_join": "9K"
            },
            "used_columns": [
              "variant_id",
              "option_id",
              "position",
              "modifier",
              "modifier_type",
              "weight_modifier",
              "weight_modifier_type",
              "point_modifier",
              "point_modifier_type",
              "status"
            ]
          }
        },
        {
          "table": {
            "table_name": "b",
            "access_type": "eq_ref",
            "possible_keys": [
              "PRIMARY"
            ],
            "key": "PRIMARY",
            "used_key_parts": [
              "variant_id",
              "lang_code"
            ],
            "key_length": "9",
            "ref": [
              "eshopuga_upgr_4122.a.variant_id",
              "const"
            ],
            "rows_examined_per_scan": 1,
            "rows_produced_per_join": 205,
            "filtered": "100.00",
            "cost_info": {
              "read_cost": "0.00",
              "eval_cost": "41.00",
              "prefix_cost": "412.01",
              "data_read_per_join": "156K"
            },
            "used_columns": [
              "variant_id",
              "lang_code",
              "variant_name"
            ]
          }
        }
      ]
    }
  }
}